Sinupret, a clinically-tested herbal combination for upper respiratory tract health, including conditions associated with sinusitis and bronchitis, had been studied by the nonprofit American Botanical Council (ABC). Sinupret contains extracts of five traditional European herbs: elder (Sambucus nigra) flowers, primrose (Primula veris) flowers with calyx, common sorrel (Rumex acetosa) herb, European vervain (Verbena officinalis) herb, and gentian (Gentiana lutea) root. Based on the review of the available scientific and clinical information from the studies, the monograph concludes that Sinupret has a relatively significant level of safety and efficacy data compared to many other natural products intended for use in maintaining the health of sinuses and the upper respiratory tract.